ARAP3

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ARAP3	AK001579, B3KMD0, B3KMD0_HUMAN,FLJ21065, DRAG1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	NM_022481	pdf		NONE	NONE	NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein.

The gene is not differential expressed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	3	6	3	3	3	6	3	4	6
Read_Max	R. aegyptiacus	Transcriptome	68	66	52	54	44	68	39	56	90
Read_Max	R. aegyptiacus	Genome	83	66	49	84	44	48	44	90	110
DESeq	H. sapiens	Genome	24.34	45.87	18.87	13.55	24.58	39.16	29.07	32.17	60.8
DESeq	R. aegyptiacus	Transcriptome	1044.45	996.74	1287.28	1190.45	1121.28	1376.57	940.98	1202.31	1686.56
DESeq	R. aegyptiacus	Genome	1389.63	1664.74	1930.3	1406.18	1616.16	1866.74	1328.07	1694.53	2256.07

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	24.34	13.55	29.07	-0.85	0.26	1.1
7h	45.87	24.58	32.17	-0.9	-0.51	0.39
23h	18.87	39.16	60.8	1.05	1.69	0.63

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	24.34	45.87	18.87	0.91	-0.37	-1.28
Ebov	13.55	24.58	39.16	0.86	1.53	0.67
Marv	29.07	32.17	60.8	0.15	1.06	0.92

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1044.45	1190.45	940.98	0.19	-0.15	-0.34
7h	996.74	1121.28	1202.31	0.17	0.27	0.1
23h	1287.28	1376.57	1686.56	0.1	0.39	0.29

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1044.45	996.74	1287.28	-0.07	0.3	0.37
Ebov	1190.45	1121.28	1376.57	-0.09	0.21	0.3
Marv	940.98	1202.31	1686.56	0.35	0.84	0.49

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material