CYTH1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| CYTH1 | AK296914,B2-1, D17S811E, cytohesin-1 | cytohesin 1 | NM_004762 |  |
NONE |  |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the PSCD family. Members of this family have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This gene is highly expressed in natural killer and peripheral T cells, and regulates the adhesiveness of integrins at the plasma membrane of lymphocytes.
The gene is not differential expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 66 | 70 | 59 | 94 | 96 | 83 | 100 | 121 | 76 |
Read_Max |  | R. aegyptiacus | Transcriptome | 74 | 75 | 51 | 56 | 50 | 86 | 44 | 78 | 114 |
Read_Max |  | R. aegyptiacus | Genome | 72 | 58 | 37 | 73 | 38 | 51 | 44 | 93 | 133 |
DESeq | | H. sapiens | Genome | 764.12 | 712.87 | 915.39 | 889.59 | 860.29 | 1137.96 | 865.92 | 794.76 | 929.59 |
DESeq | | R. aegyptiacus | Transcriptome | 438.71 | 522.01 | 401.66 | 394.74 | 466.41 | 557.9 | 410.37 | 443.85 | 583.56 |
DESeq | | R. aegyptiacus | Genome | 638.53 | 597.81 | 652.73 | 797.89 | 724.37 | 775.41 | 658.98 | 665.28 | 870.75 |