RHEB
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| RHEB | B3KWN6, D3DX13, NM_005614, NP_005605, Q15382, Q53Y56, Q99444, RHEB2, RHEB_HUMAN | Ras homolog enriched in brain | NM_005614 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
The gene is not differential expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 279 | 179 | 295 | 224 | 305 | 414 | 281 | 293 | 302 |
Read_Max |  | R. aegyptiacus | Transcriptome | 582 | 510 | 391 | 535 | 472 | 407 | 524 | 598 | 611 |
Read_Max |  | R. aegyptiacus | Genome | 553 | 470 | 285 | 434 | 302 | 219 | 389 | 639 | 526 |
DESeq | | H. sapiens | Genome | 965.05 | 878.09 | 1143.74 | 1012.79 | 1100.92 | 1440.62 | 1014.17 | 953.03 | 1362.36 |
DESeq | | R. aegyptiacus | Transcriptome | 1558.62 | 1623.04 | 1717.26 | 1773.73 | 1778.33 | 1639.62 | 2072.3 | 1878.97 | 1774.03 |
DESeq | | R. aegyptiacus | Genome | 2146.76 | 2283.54 | 2385.53 | 2161.6 | 2324.91 | 2238.78 | 2593.17 | 2367.74 | 2315.14 |