RHEB

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RHEB B3KWN6, D3DX13, NM_005614, NP_005605, Q15382, Q53Y56, Q99444, RHEB2, RHEB_HUMAN Ras homolog enriched in brain NM_005614 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.

The gene is not differential expressed.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome279 179 295 224 305 414 281 293 302
Read_Max
batR. aegyptiacusTranscriptome 582 510 391 535 472 407 524 598 611
Read_Max
bat_genomeR. aegyptiacusGenome 553 470 285 434 302 219 389 639 526
DESeq
humanH. sapiensGenome 965.05 878.09 1143.74 1012.79 1100.92 1440.62 1014.17 953.03 1362.36
DESeq
batR. aegyptiacusTranscriptome 1558.62 1623.04 1717.26 1773.73 1778.33 1639.62 2072.3 1878.97 1774.03
DESeq
bat_genomeR. aegyptiacusGenome 2146.76 2283.54 2385.53 2161.6 2324.91 2238.78 2593.17 2367.74 2315.14

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 965.05 1012.79 1014.17 0.07 0.07 0.0
7h 878.09 1100.92 953.03 0.33 0.12 -0.21
23h 1143.74 1440.62 1362.36 0.33 0.25 -0.08

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 965.05 878.09 1143.74 -0.14 0.25 0.38
Ebov 1012.79 1100.92 1440.62 0.12 0.51 0.39
Marv 1014.17 953.03 1362.36 -0.09 0.43 0.52

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1558.62 1773.73 2072.3 0.19 0.41 0.22
7h 1623.04 1778.33 1878.97 0.13 0.21 0.08
23h 1717.26 1639.62 1774.03 -0.07 0.05 0.11

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1558.62 1623.04 1717.26 0.06 0.14 0.08
Ebov 1773.73 1778.33 1639.62 0.0 -0.11 -0.12
Marv 2072.3 1878.97 1774.03 -0.14 -0.22 -0.08