CFL1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| CFL1 | Cofilin, B3KUQ1, CFL, COF1_HUMAN, NM_005507, NP_005498, P23528, Q53Y87, Q9UCA2 | cofilin 1 (non-muscle) | NM_005507 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.
This gene is highly but not differential expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 1046 | 986 | 735 | 935 | 1107 | 911 | 1259 | 1398 | 935 |
Read_Max |  | R. aegyptiacus | Transcriptome | 2480 | 2493 | 1545 | 1934 | 1651 | 1740 | 1626 | 2150 | 2777 |
Read_Max |  | R. aegyptiacus | Genome | 2931 | 2126 | 1451 | 2591 | 1535 | 1107 | 1513 | 2888 | 3314 |
DESeq | | H. sapiens | Genome | 5523.47 | 5429.78 | 4218.52 | 5702.13 | 5029.91 | 4504.09 | 5948.45 | 5940.97 | 5765.03 |
DESeq | | R. aegyptiacus | Transcriptome | 8268.82 | 9114.21 | 7755.32 | 6960.08 | 7111.42 | 6569.61 | 7519.75 | 7020.47 | 8623.0 |
DESeq | | R. aegyptiacus | Genome | 12123.42 | 9961.96 | 10555.26 | 14095.34 | 10453.71 | 9645.67 | 11452.23 | 9815.09 | 12167.34 |