VPS45

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
VPS45 Vacuolar Protein Sorting 45 Homolog (S. Cerevisiae), H1VPS45, VPS45A, SCN5,h-vps45, H1 vacuolar protein sorting 45 homolog (S. cerevisiae) NM_007259 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Vesicle mediated protein sorting plays an important role in segregation ofintracellular molecules into distinct organelles. Genetic studies in yeasthave identified more than 40 vacuolar protein sorting (VPS) genes involvedin vesicle transport to vacuoles. This gene is a member of the Sec1 domainfamily, and shows a high degree of sequence similarity to mouse, rat andyeast Vps45. The exact function of this gene is not known, but its highexpression in peripheral blood mononuclear cells suggests a role intrafficking proteins, including inflammatory mediators. Multiplealternatively spliced transcript variants have been found for this gene.

Expression in all samples, some variation in human cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome78 112 76 81 140 156 107 149 70
Read_Max
batR. aegyptiacusTranscriptome 47 41 31 50 52 45 48 56 52
Read_Max
bat_genomeR. aegyptiacusGenome 61 67 39 42 46 28 43 86 76
DESeq
humanH. sapiensGenome 1068.56 1216.69 1047.44 1008.22 1184.66 1449.83 1019.43 1124.89 890.45
DESeq
batR. aegyptiacusTranscriptome 332.02 321.41 311.27 384.67 400.71 252.5 325.82 341.4 364.88
DESeq
bat_genomeR. aegyptiacusGenome 1045.88 1212.96 1095.69 911.45 1118.37 787.16 1031.2 1181.49 1043.7

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1068.56 1008.22 1019.43 -0.08 -0.07 0.02
7h 1216.69 1184.66 1124.89 -0.04 -0.11 -0.07
23h 1047.44 1449.83 890.45 0.47 -0.23 -0.7

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1068.56 1216.69 1047.44 0.19 -0.03 -0.22
Ebov 1008.22 1184.66 1449.83 0.23 0.52 0.29
Marv 1019.43 1124.89 890.45 0.14 -0.2 -0.34

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 332.02 384.67 325.82 0.21 -0.03 -0.24
7h 321.41 400.71 341.4 0.32 0.09 -0.23
23h 311.27 252.5 364.88 -0.3 0.23 0.53

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 332.02 321.41 311.27 -0.05 -0.09 -0.05
Ebov 384.67 400.71 252.5 0.06 -0.61 -0.67
Marv 325.82 341.4 364.88 0.07 0.16 0.1