RNF41

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RNF41 FLRF, NRDP1,SBBI03 ring finger protein 41, E3 ubiquitin protein ligase NM_005785 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes an E3 ubiquitin ligase. The encoded protein plays a role in type 1 cytokine receptor signaling by controlling the balance between JAK2-associated cytokine receptor degradation and ectodomain shedding. Alternative splicing results in multiple transcript variants.

The gene RNF41 is weakly expressed in human cells and moderately expressed in bat cells datasets, without significant changes in expression profiles.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome169 144 109 149 190 117 217 211 136
Read_Max
batR. aegyptiacusTranscriptome 180 149 175 155 117 161 118 185 132
Read_Max
bat_genomeR. aegyptiacusGenome 193 149 149 160 133 110 124 227 227
DESeq
humanH. sapiensGenome 1871.25 1850.03 1690.79 1908.22 1929.32 1457.73 1893.13 1886.67 2248.55
DESeq
batR. aegyptiacusTranscriptome 710.08 646.37 876.84 618.16 667.91 724.71 658.43 668.58 631.67
DESeq
bat_genomeR. aegyptiacusGenome 2009.25 1703.07 2234.9 1948.31 1913.05 2465.92 1850.98 1850.74 2026.61

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1871.25 1908.22 1893.13 0.03 0.02 -0.01
7h 1850.03 1929.32 1886.67 0.06 0.03 -0.03
23h 1690.79 1457.73 2248.55 -0.21 0.41 0.63

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1871.25 1850.03 1690.79 -0.02 -0.15 -0.13
Ebov 1908.22 1929.32 1457.73 0.02 -0.39 -0.4
Marv 1893.13 1886.67 2248.55 -0.0 0.25 0.25

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 710.08 618.16 658.43 -0.2 -0.11 0.09
7h 646.37 667.91 668.58 0.05 0.05 0.0
23h 876.84 724.71 631.67 -0.27 -0.47 -0.2

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 710.08 646.37 876.84 -0.14 0.3 0.44
Ebov 618.16 667.91 724.71 0.11 0.23 0.12
Marv 658.43 668.58 631.67 0.02 -0.06 -0.08