PSD

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
PSD KIAA2011, TYL, PSD1, EFA6A, EFA6 pleckstrin and Sec7 domain containing pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants.

It is weakly expressed in human cells and no homolog was found in bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome3 2 2 2 2 3 2 2 3
Read_Max
batR. aegyptiacusTranscriptome NA 9 2 2 1 NA 2 1 NA
Read_Max
bat_genomeR. aegyptiacusGenome 6 4 5 6 2 2 2 3 6
DESeq
humanH. sapiensGenome 5.06 5.08 2.99 3.28 4.25 18.11 2.75 4.2 7.52
DESeq
batR. aegyptiacusTranscriptome 1.0 9.17 3.44 2.83 2.1 1.0 3.22 1.83 1.0
DESeq
bat_genomeR. aegyptiacusGenome 18.05 18.25 27.89 25.67 6.7 11.75 15.74 9.52 17.12

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 5.06 3.28 2.75 -0.63 -0.88 -0.25
7h 5.08 4.25 4.2 -0.26 -0.27 -0.02
23h 2.99 18.11 7.52 2.6 1.33 -1.27

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 5.06 5.08 2.99 0.01 -0.76 -0.76
Ebov 3.28 4.25 18.11 0.37 2.47 2.09
Marv 2.75 4.2 7.52 0.61 1.45 0.84

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 2.83 3.22 1.5 1.69 0.19
7h 9.17 2.1 1.83 -2.13 -2.33 -0.2
23h 3.44 1.0 1.0 -1.78 -1.78 0.0

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 9.17 3.44 3.2 1.78 -1.41
Ebov 2.83 2.1 1.0 -0.43 -1.5 -1.07
Marv 3.22 1.83 1.0 -0.82 -1.69 -0.87