SH3KBP1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
SH3KBP1	AK307276,CIN85	SH3-domain kinase binding protein 1	NM_031892	pdf		NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes an adapter protein that contains three N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis.

1The gene is not significantly differential expressed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	207	205	312	248	348	273	287	269	394
Read_Max	R. aegyptiacus	Transcriptome	194	165	111	139	130	166	174	176	248
Read_Max	R. aegyptiacus	Genome	193	145	114	142	103	100	152	207	265
DESeq	H. sapiens	Genome	3276.73	3106.51	3675.44	3464.11	2903.23	3363.18	3282.62	2797.13	4543.94
DESeq	R. aegyptiacus	Transcriptome	1773.7	1578.56	1404.55	1480.72	1541.79	1843.65	1785.3	1569.14	2095.05
DESeq	R. aegyptiacus	Genome	1628.54	1306.05	1382.45	1562.2	1387.35	1685.28	1600.21	1412.24	1888.76

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3276.73	3464.11	3282.62	0.08	0.0	-0.08
7h	3106.51	2903.23	2797.13	-0.1	-0.15	-0.05
23h	3675.44	3363.18	4543.94	-0.13	0.31	0.43

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3276.73	3106.51	3675.44	-0.08	0.17	0.24
Ebov	3464.11	2903.23	3363.18	-0.25	-0.04	0.21
Marv	3282.62	2797.13	4543.94	-0.23	0.47	0.7

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1773.7	1480.72	1785.3	-0.26	0.01	0.27
7h	1578.56	1541.79	1569.14	-0.03	-0.01	0.03
23h	1404.55	1843.65	2095.05	0.39	0.58	0.18

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1773.7	1578.56	1404.55	-0.17	-0.34	-0.17
Ebov	1480.72	1541.79	1843.65	0.06	0.32	0.26
Marv	1785.3	1569.14	2095.05	-0.19	0.23	0.42

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material