STAMBP

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
STAMBP AMSH, MICCAP STAM binding protein NM_006463 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

The gene STAMBP is moderately expressed in human cells and bat cells datasets without significant changes in expression levels.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome146 138 153 128 214 153 188 171 131
Read_Max
batR. aegyptiacusTranscriptome 103 100 73 140 108 107 68 144 122
Read_Max
bat_genomeR. aegyptiacusGenome 114 136 70 96 96 65 60 177 140
DESeq
humanH. sapiensGenome 2210.19 1963.24 2082.95 2226.47 2241.49 1963.04 2279.1 1957.01 1944.09
DESeq
batR. aegyptiacusTranscriptome 563.05 548.34 677.73 793.05 837.65 682.37 591.69 802.42 636.91
DESeq
bat_genomeR. aegyptiacusGenome 936.74 1145.42 1055.53 868.99 1265.7 1066.52 954.73 1258.41 1026.57

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2210.19 2226.47 2279.1 0.01 0.04 0.03
7h 1963.24 2241.49 1957.01 0.19 -0.0 -0.2
23h 2082.95 1963.04 1944.09 -0.09 -0.1 -0.01

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2210.19 1963.24 2082.95 -0.17 -0.09 0.09
Ebov 2226.47 2241.49 1963.04 0.01 -0.18 -0.19
Marv 2279.1 1957.01 1944.09 -0.22 -0.23 -0.01

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 563.05 793.05 591.69 0.49 0.07 -0.42
7h 548.34 837.65 802.42 0.61 0.55 -0.06
23h 677.73 682.37 636.91 0.01 -0.09 -0.1

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 563.05 548.34 677.73 -0.04 0.27 0.31
Ebov 793.05 837.65 682.37 0.08 -0.22 -0.3
Marv 591.69 802.42 636.91 0.44 0.11 -0.33