SMAD7
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| SMAD7 | B3KYA8, B3KYA8_HUMAN, NM_001190823, NP_001177752 | SMAD family member 7 | NM_005904 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3).
This gene is not differentially expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 73 | 46 | 32 | 64 | 49 | 58 | 58 | 55 | 51 |
Read_Max |  | R. aegyptiacus | Transcriptome | 141 | 101 | 65 | 75 | 60 | 86 | 87 | 133 | 132 |
Read_Max |  | R. aegyptiacus | Genome | 154 | 118 | 143 | 93 | 116 | 109 | 158 | 274 | 290 |
DESeq | | H. sapiens | Genome | 782.39 | 546.63 | 361.4 | 863.36 | 626.16 | 462.89 | 650.13 | 515.78 | 593.6 |
DESeq | | R. aegyptiacus | Transcriptome | 776.45 | 710.81 | 581.23 | 563.22 | 586.87 | 563.03 | 758.55 | 659.49 | 732.26 |
DESeq | | R. aegyptiacus | Genome | 1711.9 | 1382.72 | 1674.78 | 1735.01 | 1626.21 | 1689.2 | 2087.13 | 1706.42 | 1808.28 |