VPS25

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
VPS25 DERP9, EAP20, FAP20,MGC10540, DERP9 vacuolar protein sorting 25 homolog (S. cerevisiae) NM_032353 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a protein that is a subunit of the endosomal sorting complex required for transport II (ESCRT-II). This protein complex functions in sorting of ubiquitinated membrane proteins during endocytosis. A pseudogene of this gene is present on chromosome 1.

The gene VPS25 is expressed in all human cells and bat cells datasets, usually it goes down at 23 h datasets but not in the bat cells Marburg dataset.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome105 122 90 144 163 138 143 204 88
Read_Max
batR. aegyptiacusTranscriptome 67 123 37 77 62 58 46 88 85
Read_Max
bat_genomeR. aegyptiacusGenome 95 89 73 118 55 51 60 136 107
DESeq
humanH. sapiensGenome 567.25 691.45 552.02 857.65 715.58 607.64 756.27 805.15 529.45
DESeq
batR. aegyptiacusTranscriptome 78.29 159.85 74.29 88.9 88.61 88.26 78.87 96.01 98.97
DESeq
bat_genomeR. aegyptiacusGenome 440.87 430.79 531.11 485.84 450.92 489.53 437.44 475.77 536.83

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 567.25 857.65 756.27 0.6 0.41 -0.18
7h 691.45 715.58 805.15 0.05 0.22 0.17
23h 552.02 607.64 529.45 0.14 -0.06 -0.2

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 567.25 691.45 552.02 0.29 -0.04 -0.32
Ebov 857.65 715.58 607.64 -0.26 -0.5 -0.24
Marv 756.27 805.15 529.45 0.09 -0.51 -0.6

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 78.29 88.9 78.87 0.18 0.01 -0.17
7h 159.85 88.61 96.01 -0.85 -0.74 0.12
23h 74.29 88.26 98.97 0.25 0.41 0.17

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 78.29 159.85 74.29 1.03 -0.08 -1.11
Ebov 88.9 88.61 88.26 -0.0 -0.01 -0.01
Marv 78.87 96.01 98.97 0.28 0.33 0.04