AGAP1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
AGAP1	ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1, CENTG2,KIAA1099, GGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	NM_014914	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene.

This gene is expressed in all samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	49	52	42	49	64	67	48	69	49
Read_Max	R. aegyptiacus	Transcriptome	220	181	108	154	118	173	181	171	210
Read_Max	R. aegyptiacus	Genome	271	162	98	197	119	101	174	206	223
DESeq	H. sapiens	Genome	1029.99	1047.39	940.21	926.09	965.16	1097.16	843.12	908.26	952.43
DESeq	R. aegyptiacus	Transcriptome	1922.4	1847.24	1319.04	1486.21	1612.97	1780.77	2162.41	1476.61	1699.68
DESeq	R. aegyptiacus	Genome	2868.64	2149.37	2219.28	2921.96	2401.92	2597.77	3019.37	2062.45	2453.85

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1029.99	926.09	843.12	-0.15	-0.29	-0.14
7h	1047.39	965.16	908.26	-0.12	-0.21	-0.09
23h	940.21	1097.16	952.43	0.22	0.02	-0.2

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1029.99	1047.39	940.21	0.02	-0.13	-0.16
Ebov	926.09	965.16	1097.16	0.06	0.24	0.18
Marv	843.12	908.26	952.43	0.11	0.18	0.07

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1922.4	1486.21	2162.41	-0.37	0.17	0.54
7h	1847.24	1612.97	1476.61	-0.2	-0.32	-0.13
23h	1319.04	1780.77	1699.68	0.43	0.37	-0.07

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1922.4	1847.24	1319.04	-0.06	-0.54	-0.49
Ebov	1486.21	1612.97	1780.77	0.12	0.26	0.14
Marv	2162.41	1476.61	1699.68	-0.55	-0.35	0.2

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material