EPN1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
EPN1		epsin 1	NM_013333	pdf		NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene binds clathrin and is involved in the endocytosis of clathrin-coated vesicles. Three transcript variants encoding different isoforms have been found for this gene.

The gene is moderately equally expressed in all human cells samples as well as in the bat cells homolog.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	245	239	200	249	258	340	332	386	168
Read_Max	R. aegyptiacus	Transcriptome	46	42	41	40	30	45	32	51	44
Read_Max	R. aegyptiacus	Genome	179	170	104	166	90	90	92	185	182
DESeq	H. sapiens	Genome	2114.8	2021.37	1658.02	2018.87	1624.46	2464.41	2196.64	2298.33	1776.64
DESeq	R. aegyptiacus	Transcriptome	254.72	261.51	302.72	216.18	235.35	283.3	254.63	224.9	230.17
DESeq	R. aegyptiacus	Genome	1777.22	1611.8	1755.12	1888.07	1567.05	1780.58	1723.91	1506.6	1765.47

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2114.8	2018.87	2196.64	-0.07	0.05	0.12
7h	2021.37	1624.46	2298.33	-0.32	0.19	0.5
23h	1658.02	2464.41	1776.64	0.57	0.1	-0.47

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2114.8	2021.37	1658.02	-0.07	-0.35	-0.29
Ebov	2018.87	1624.46	2464.41	-0.31	0.29	0.6
Marv	2196.64	2298.33	1776.64	0.07	-0.31	-0.37

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	254.72	216.18	254.63	-0.24	-0.0	0.24
7h	261.51	235.35	224.9	-0.15	-0.22	-0.07
23h	302.72	283.3	230.17	-0.1	-0.4	-0.3

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	254.72	261.51	302.72	0.04	0.25	0.21
Ebov	216.18	235.35	283.3	0.12	0.39	0.27
Marv	254.63	224.9	230.17	-0.18	-0.15	0.03

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material