RAB11FIP4

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
RAB11FIP4	RAB11-FIP4, KIAA1821, MGC11316, FLJ00131	RAB11 family interacting protein 4 (class II)	NM_032932	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP4 is one of many proteins that interact with and regulate Rab GTPases.

This gene is uniformly expressed in human cells. The homolog is very lowly expressed, slightly enriched in Marburg infected cells after 23 h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	74	71	83	90	94	75	115	98	106
Read_Max	R. aegyptiacus	Transcriptome	6	5	8	5	11	20	3	15	10
Read_Max	R. aegyptiacus	Genome	7	5	5	5	5	5	3	13	13
DESeq	H. sapiens	Genome	1934.17	1738.86	1619.3	2002.9	1770.79	1164.28	2021.2	1805.93	2642.17
DESeq	R. aegyptiacus	Transcriptome	35.45	16.43	32.76	38.54	59.04	61.31	22.14	62.97	56.98
DESeq	R. aegyptiacus	Genome	63.59	88.53	58.02	43.45	73.66	109.65	39.36	80.09	123.29

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1934.17	2002.9	2021.2	0.05	0.06	0.01
7h	1738.86	1770.79	1805.93	0.03	0.05	0.03
23h	1619.3	1164.28	2642.17	-0.48	0.71	1.18

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1934.17	1738.86	1619.3	-0.15	-0.26	-0.1
Ebov	2002.9	1770.79	1164.28	-0.18	-0.78	-0.6
Marv	2021.2	1805.93	2642.17	-0.16	0.39	0.55

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	35.45	38.54	22.14	0.12	-0.68	-0.8
7h	16.43	59.04	62.97	1.85	1.94	0.09
23h	32.76	61.31	56.98	0.9	0.8	-0.11

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	35.45	16.43	32.76	-1.11	-0.11	1.0
Ebov	38.54	59.04	61.31	0.62	0.67	0.05
Marv	22.14	62.97	56.98	1.51	1.36	-0.14

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material