ZFYVE9

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
ZFYVE9	MADHIP, SMADIP,sara,SMADIP, SARA, PPP1R173	zinc finger, FYVE domain containing 9	NM_007324	pdf

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Description

Homo sapiens zinc finger, FYVE domain containing 9 (ZFYVE9). This geneencodes a double zinc finger motif-containing protein that participates inthe transforming growth factor-beta (TGFB) signalling pathway. The encodedprotein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to theTGFB receptor. There are multiple pseudogenes for this gene on chromosomes2, 15, and X. Alternative splicing results in multiple transcript variants.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	109	132	172	114	232	195	141	144	116
Read_Max	R. aegyptiacus	Transcriptome	67	92	50	82	66	68	53	75	63
Read_Max	R. aegyptiacus	Genome	98	84	45	85	56	46	53	105	76
DESeq	H. sapiens	Genome	1848.93	2194.75	2507.88	2047.39	2388.64	1659.06	1987.87	2077.71	1826.66
DESeq	R. aegyptiacus	Transcriptome	1157.87	1151.04	1091.83	1364.43	1314.01	1281.62	1044.44	1283.28	1137.25
DESeq	R. aegyptiacus	Genome	1488.46	1631.88	1317.73	1532.57	1607.23	1601.74	1302.21	1504.22	1390.46

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1848.93	2047.39	1987.87	0.15	0.1	-0.04
7h	2194.75	2388.64	2077.71	0.12	-0.08	-0.2
23h	2507.88	1659.06	1826.66	-0.6	-0.46	0.14

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1848.93	2194.75	2507.88	0.25	0.44	0.19
Ebov	2047.39	2388.64	1659.06	0.22	-0.3	-0.53
Marv	1987.87	2077.71	1826.66	0.06	-0.12	-0.19

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1157.87	1364.43	1044.44	0.24	-0.15	-0.39
7h	1151.04	1314.01	1283.28	0.19	0.16	-0.03
23h	1091.83	1281.62	1137.25	0.23	0.06	-0.17

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1157.87	1151.04	1091.83	-0.01	-0.08	-0.08
Ebov	1364.43	1314.01	1281.62	-0.05	-0.09	-0.04
Marv	1044.44	1283.28	1137.25	0.3	0.12	-0.17

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material