AGAP3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
AGAP3 AGAP-3, CENTG3, CRAG, MRIP-1, cnt-g3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 NM_031946 pdf

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Description

Homo sapiens ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 (AGAP3), transcript variant 2, mRNA.

The gene is upregulated in early human cells Ebola virus infection then goes slightly down again. In Marburg virus infected cells it is also upregulated, but not significantly, and also transiently, i.e., down again after 23 h. In bat cells, expression upon Ebola virus infection goes down and then up again, albeit not significantly, while in Marburg virus infected cells it goes two-fold up at 7h and stays at this level.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome118 103 106 94 164 180 115 144 82
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 78 62 54 82 51 57 38 119 99
DESeq
humanH. sapiensGenome 1418.66 1646.05 1435.63 1482.75 1465.94 2252.54 1507.16 1816.32 1491.75
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 366.1 324.92 393.87 473.99 401.81 434.7 312.62 394.89 400.7

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1418.66 1482.75 1507.16 0.06 0.09 0.02
7h 1646.05 1465.94 1816.32 -0.17 0.14 0.31
23h 1435.63 2252.54 1491.75 0.65 0.06 -0.59

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1418.66 1646.05 1435.63 0.21 0.02 -0.2
Ebov 1482.75 1465.94 2252.54 -0.02 0.6 0.62
Marv 1507.16 1816.32 1491.75 0.27 -0.01 -0.28

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA