DIAPH3
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| DIAPH3 | DRF3, FLJ34705, AN, NSDAN | diaphanous-related formin 3 | NM_001042517 |  |
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NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the diaphanous subfamily of the formin family. Members of this family are involved in actin remodeling and regulate cell movement and adhesion. Mutations in this gene are associated with autosomal dominant auditory neuropathy 1. Multiple transcript variants encoding different isoforms have been found for this gene. Acts in a Rho-dependent manner to recruit profiling to the membrane, where it promotes actin polymerization (uniprot).
The moderate expression of this gene is upregulated 23 h after Ebola infection. All other samples have an equal expression or similar to the respective Mock samples.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 105 | 134 | 145 | 101 | 196 | 470 | 114 | 132 | 106 |
Read_Max |  | R. aegyptiacus | Transcriptome | 392 | 372 | 109 | 366 | 309 | 259 | 348 | 395 | 191 |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 2472.01 | 2590.46 | 2449.31 | 2428.37 | 2841.45 | 7254.36 | 2171.2 | 2352.69 | 2406.21 |
DESeq | | R. aegyptiacus | Transcriptome | 6527.21 | 6201.43 | 2003.1 | 5387.88 | 5725.04 | 4197.0 | 7048.09 | 5249.08 | 2922.53 |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |