DNM1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| DNM1 | DNM | dynamin 1 | NM_004408 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. The gene is lowly but stably expressed in human, and shows comparibly large intron retention at a central intron. The bat homologs are almost not expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 16 | 16 | 22 | 18 | 14 | 19 | 12 | 23 | 19 |
Read_Max |  | R. aegyptiacus | Transcriptome | 214 | 208 | 132 | 221 | 174 | 211 | 150 | 228 | 276 |
Read_Max |  | R. aegyptiacus | Genome | 3 | 3 | 9 | 3 | 5 | 5 | 4 | 4 | 5 |
DESeq | | H. sapiens | Genome | 435.33 | 412.01 | 707.89 | 338.64 | 352.19 | 214.18 | 302.76 | 494.2 | 712.12 |
DESeq | | R. aegyptiacus | Transcriptome | 2673.49 | 2593.36 | 2188.77 | 2549.3 | 2612.79 | 2958.73 | 2439.39 | 2708.49 | 2940.9 |
DESeq | | R. aegyptiacus | Genome | 14.61 | 23.73 | 60.25 | 27.65 | 23.44 | 48.3 | 16.87 | 20.62 | 42.81 |