IQSEC1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
IQSEC1 ARF-GEP100, ARFGEP100, BRAG2, GEP100,KIAA0763, ARF-GEP100 IQ motif and Sec7 domain 1 NM_014869 pdf

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Description

Homo sapiens IQ motif and Sec7 domain 1 (IQSEC1), transcript variant 2, mRNA. Gene is highly expressed in human and twofold downregulated in MARV 23h. The bat homolog is upregulated in MARV 7h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome404 437 276 368 407 408 507 472 189
Read_Max
batR. aegyptiacusTranscriptome 128 118 71 96 87 104 84 123 126
Read_Max
bat_genomeR. aegyptiacusGenome 149 113 68 116 73 64 70 155 166
DESeq
humanH. sapiensGenome 13055.22 11976.35 10308.51 11866.39 10869.34 12036.42 12021.34 10853.78 7344.94
DESeq
batR. aegyptiacusTranscriptome 1415.8 1360.72 1317.82 1388.24 1378.62 1424.05 1176.81 1312.19 1399.66
DESeq
bat_genomeR. aegyptiacusGenome 3382.56 3364.16 3265.88 3360.41 3431.0 3580.74 3101.46 3099.63 3518.09

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 13055.22 11866.39 12021.34 -0.14 -0.12 0.02
7h 11976.35 10869.34 10853.78 -0.14 -0.14 -0.0
23h 10308.51 12036.42 7344.94 0.22 -0.49 -0.71

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 13055.22 11976.35 10308.51 -0.12 -0.34 -0.22
Ebov 11866.39 10869.34 12036.42 -0.13 0.02 0.15
Marv 12021.34 10853.78 7344.94 -0.15 -0.71 -0.56

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1415.8 1388.24 1176.81 -0.03 -0.27 -0.24
7h 1360.72 1378.62 1312.19 0.02 -0.05 -0.07
23h 1317.82 1424.05 1399.66 0.11 0.09 -0.02

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1415.8 1360.72 1317.82 -0.06 -0.1 -0.05
Ebov 1388.24 1378.62 1424.05 -0.01 0.04 0.05
Marv 1176.81 1312.19 1399.66 0.16 0.25 0.09