CAV2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CAV2 Caveolae Protein, 20-KD,CAV caveolin 2 NM_001233 pdf

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Description

Description: Homo sapiens caveolin 2 (CAV2), transcript variant 1, mRNA. The protein encoded by this gene is a major component of the inner surface of caveolae, small invaginations of the plasma membrane, and is involved in essential cellular functions, including signal transduction, lipid metabolism, cellular growth control and apoptosis. This protein may function as a tumor suppressor. This gene and related family member (CAV1) are located next to each other on chromosome 7, and express colocalizing proteins that form a stable hetero-oligomeric complex. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Additional isoforms resulting from the use of alternate in-frame translation initiation codons have also been described, and shown to have preferential localization in the cell (PMID:11238462). [provided by RefSeq, May 2011].

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome34 29 33 34 35 29 43 67 66
Read_Max
batR. aegyptiacusTranscriptome 261 299 165 266 238 170 230 266 185
Read_Max
bat_genomeR. aegyptiacusGenome 414 300 150 317 240 156 237 396 311
DESeq
humanH. sapiensGenome 322.69 305.94 316.72 391.11 310.73 176.02 362.41 355.11 727.35
DESeq
batR. aegyptiacusTranscriptome 1008.33 1046.66 694.83 1028.38 1044.62 747.81 1151.23 956.92 664.9
DESeq
bat_genomeR. aegyptiacusGenome 2517.15 2511.71 1466.13 2491.42 2733.41 2041.66 3146.44 2461.3 1851.94

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 322.69 391.11 362.41 0.28 0.17 -0.11
7h 305.94 310.73 355.11 0.02 0.22 0.19
23h 316.72 176.02 727.35 -0.85 1.2 2.05

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 322.69 305.94 316.72 -0.08 -0.03 0.05
Ebov 391.11 310.73 176.02 -0.33 -1.15 -0.82
Marv 362.41 355.11 727.35 -0.03 1.01 1.03

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1008.33 1028.38 1151.23 0.03 0.19 0.16
7h 1046.66 1044.62 956.92 -0.0 -0.13 -0.13
23h 694.83 747.81 664.9 0.11 -0.06 -0.17

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1008.33 1046.66 694.83 0.05 -0.54 -0.59
Ebov 1028.38 1044.62 747.81 0.02 -0.46 -0.48
Marv 1151.23 956.92 664.9 -0.27 -0.79 -0.53