CLIP1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CLIP1 CLIP, CLIP-170, CLIP170, CYLN1, RSN,CYLN1, CLIP CAP-GLY domain containing linker protein 1 NM_002956 pdf

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Description

The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. Gene is uniformely expressed in human EBOV and MARV, downregulated in human wt 23h. Bat homolog is also downregulated in bat wt 23h, upregulated in EBOV 23h and MARV 7h and 23h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome294 232 282 290 492 442 357 375 333
Read_Max
batR. aegyptiacusTranscriptome 128 88 92 126 100 235 106 160 174
Read_Max
bat_genomeR. aegyptiacusGenome 243 202 122 176 161 222 146 293 327
DESeq
humanH. sapiensGenome 6784.85 5901.98 4858.89 7700.61 6768.81 7559.66 7440.57 5898.61 6967.63
DESeq
batR. aegyptiacusTranscriptome 1590.55 1486.89 1643.97 1825.93 2019.25 2876.61 1548.36 1798.83 1836.14
DESeq
bat_genomeR. aegyptiacusGenome 5026.57 5928.8 5038.85 5013.45 6436.74 9770.99 5433.74 5809.92 5618.33

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 6784.85 7700.61 7440.57 0.18 0.13 -0.05
7h 5901.98 6768.81 5898.61 0.2 -0.0 -0.2
23h 4858.89 7559.66 6967.63 0.64 0.52 -0.12

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 6784.85 5901.98 4858.89 -0.2 -0.48 -0.28
Ebov 7700.61 6768.81 7559.66 -0.19 -0.03 0.16
Marv 7440.57 5898.61 6967.63 -0.34 -0.09 0.24

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1590.55 1825.93 1548.36 0.2 -0.04 -0.24
7h 1486.89 2019.25 1798.83 0.44 0.27 -0.17
23h 1643.97 2876.61 1836.14 0.81 0.16 -0.65

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1590.55 1486.89 1643.97 -0.1 0.05 0.14
Ebov 1825.93 2019.25 2876.61 0.15 0.66 0.51
Marv 1548.36 1798.83 1836.14 0.22 0.25 0.03