RAB11B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RAB11B H-YPT3 RAB11B, member RAS oncogene family NM_004218 pdf

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Description

The Ras superfamily of small GTP-binding proteins, which includes the Ras (see MIM 190020), Ral (see MIM 179550), Rho (see MIM 165390), Rap (see MIM 179520), and Rab (see MIM 179508) families, is involved in controlling a diverse set of essential cellular functions. The Rab family, including RAB11B, appears to play a critical role in regulating exocytotic and endocytotic pathways. Gene is 2-fold downregulated in MARV 23h. In contrast, the bat homolog is upregulated in MARV23 only.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome68 65 50 77 59 60 115 120 44
Read_Max
batR. aegyptiacusTranscriptome 294 266 254 248 198 196 171 255 352
Read_Max
bat_genomeR. aegyptiacusGenome 318 252 204 252 170 116 143 301 378
DESeq
humanH. sapiensGenome 670.76 640.46 455.71 696.82 463.57 476.05 691.36 672.45 476.17
DESeq
batR. aegyptiacusTranscriptome 1083.1 1144.69 1264.07 1083.32 1026.0 874.85 956.56 993.28 1412.78
DESeq
bat_genomeR. aegyptiacusGenome 2274.81 1861.88 2236.02 2294.91 2058.15 1968.56 2050.02 1761.93 2548.03

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 670.76 696.82 691.36 0.05 0.04 -0.01
7h 640.46 463.57 672.45 -0.47 0.07 0.54
23h 455.71 476.05 476.17 0.06 0.06 0.0

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 670.76 640.46 455.71 -0.07 -0.56 -0.49
Ebov 696.82 463.57 476.05 -0.59 -0.55 0.04
Marv 691.36 672.45 476.17 -0.04 -0.54 -0.5

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1083.1 1083.32 956.56 0.0 -0.18 -0.18
7h 1144.69 1026.0 993.28 -0.16 -0.2 -0.05
23h 1264.07 874.85 1412.78 -0.53 0.16 0.69

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1083.1 1144.69 1264.07 0.08 0.22 0.14
Ebov 1083.32 1026.0 874.85 -0.08 -0.31 -0.23
Marv 956.56 993.28 1412.78 0.05 0.56 0.51