RPS6KA1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
RPS6KA1	HU-1, MAPKAPK1A, RSK, RSK1,RSK, HU-1, p90Rsk	ribosomal protein S6 kinase, 90kDa, polypeptide 1	NM_002953	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The ribosomal protein S6 kinase, 90kDa, polypeptide 1 (EC:2.7.11.1) is involved in the MAPK, mTOR and Neurotrophin signaling pathways. Oocyte meiosis, Long-term potentiation and Progesterone-mediated oocyte maturation.No direct evidence of differential gene expression in the conditions tested.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	25	32	47	31	45	67	33	57	49
Read_Max	R. aegyptiacus	Transcriptome	55	54	38	46	44	58	36	60	56
Read_Max	R. aegyptiacus	Genome	58	45	32	45	32	36	34	79	60
DESeq	H. sapiens	Genome	407.93	501.76	598.68	513.17	509.91	760.29	466.8	582.93	752.36
DESeq	R. aegyptiacus	Transcriptome	567.25	589.18	498.17	541.24	494.89	638.74	461.54	520.69	553.82
DESeq	R. aegyptiacus	Genome	686.65	691.82	633.76	759.37	639.54	787.16	633.11	685.11	763.72

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	407.93	513.17	466.8	0.33	0.19	-0.14
7h	501.76	509.91	582.93	0.02	0.22	0.19
23h	598.68	760.29	752.36	0.34	0.33	-0.02

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	407.93	501.76	598.68	0.3	0.55	0.25
Ebov	513.17	509.91	760.29	-0.01	0.57	0.58
Marv	466.8	582.93	752.36	0.32	0.69	0.37

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	567.25	541.24	461.54	-0.07	-0.3	-0.23
7h	589.18	494.89	520.69	-0.25	-0.18	0.07
23h	498.17	638.74	553.82	0.36	0.15	-0.21

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	567.25	589.18	498.17	0.05	-0.19	-0.24
Ebov	541.24	494.89	638.74	-0.13	0.24	0.37
Marv	461.54	520.69	553.82	0.17	0.26	0.09

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material