SNF8

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SNF8 SNF8, ESCRT-II Complex Subunit, EAP30, EAP30 Subunit Of ELL Complex, VPS22,EAP30, Dot3 SNF8, ESCRT-II complex subunit NM_007241 pdf

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Description

SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 Expressed in all samples, some variation in expression level.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome102 143 148 126 208 211 174 174 162
Read_Max
batR. aegyptiacusTranscriptome 266 288 270 233 238 228 223 301 321
Read_Max
bat_genomeR. aegyptiacusGenome 393 290 252 390 250 164 253 439 475
DESeq
humanH. sapiensGenome 828.05 999.46 969.0 954.61 931.83 1032.68 966.8 954.63 963.3
DESeq
batR. aegyptiacusTranscriptome 1269.61 1426.98 1713.59 1148.33 1423.52 1350.91 1436.0 1364.24 1470.51
DESeq
bat_genomeR. aegyptiacusGenome 1701.59 1481.29 1980.51 2027.3 1849.43 1682.67 1814.99 1744.48 1883.62

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 828.05 954.61 966.8 0.21 0.22 0.02
7h 999.46 931.83 954.63 -0.1 -0.07 0.03
23h 969.0 1032.68 963.3 0.09 -0.01 -0.1

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 828.05 999.46 969.0 0.27 0.23 -0.04
Ebov 954.61 931.83 1032.68 -0.03 0.11 0.15
Marv 966.8 954.63 963.3 -0.02 -0.01 0.01

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1269.61 1148.33 1436.0 -0.14 0.18 0.32
7h 1426.98 1423.52 1364.24 -0.0 -0.06 -0.06
23h 1713.59 1350.91 1470.51 -0.34 -0.22 0.12

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1269.61 1426.98 1713.59 0.17 0.43 0.26
Ebov 1148.33 1423.52 1350.91 0.31 0.23 -0.08
Marv 1436.0 1364.24 1470.51 -0.07 0.03 0.11