SNF8

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
SNF8	SNF8, ESCRT-II Complex Subunit, EAP30, EAP30 Subunit Of ELL Complex, VPS22,EAP30, Dot3	SNF8, ESCRT-II complex subunit	NM_007241	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL; MIM 600284) (Slagsvold et al., 2005 Expressed in all samples, some variation in expression level.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	102	143	148	126	208	211	174	174	162
Read_Max	R. aegyptiacus	Transcriptome	266	288	270	233	238	228	223	301	321
Read_Max	R. aegyptiacus	Genome	393	290	252	390	250	164	253	439	475
DESeq	H. sapiens	Genome	828.05	999.46	969.0	954.61	931.83	1032.68	966.8	954.63	963.3
DESeq	R. aegyptiacus	Transcriptome	1269.61	1426.98	1713.59	1148.33	1423.52	1350.91	1436.0	1364.24	1470.51
DESeq	R. aegyptiacus	Genome	1701.59	1481.29	1980.51	2027.3	1849.43	1682.67	1814.99	1744.48	1883.62

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	828.05	954.61	966.8	0.21	0.22	0.02
7h	999.46	931.83	954.63	-0.1	-0.07	0.03
23h	969.0	1032.68	963.3	0.09	-0.01	-0.1

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	828.05	999.46	969.0	0.27	0.23	-0.04
Ebov	954.61	931.83	1032.68	-0.03	0.11	0.15
Marv	966.8	954.63	963.3	-0.02	-0.01	0.01

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1269.61	1148.33	1436.0	-0.14	0.18	0.32
7h	1426.98	1423.52	1364.24	-0.0	-0.06	-0.06
23h	1713.59	1350.91	1470.51	-0.34	-0.22	0.12

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1269.61	1426.98	1713.59	0.17	0.43	0.26
Ebov	1148.33	1423.52	1350.91	0.31	0.23	-0.08
Marv	1436.0	1364.24	1470.51	-0.07	0.03	0.11

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material