HSPA8

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
HSPA8 Heat Shock 70kDa Protein 8, NIP71, HSP73,HSC71, HSC70 heat shock 70kDa protein 8 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Very high expression in all samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome3641 5559 4886 3326 7681 10762 4137 7031 5003
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 11437 11244 4528 9144 7769 7628 6688 15145 9763
DESeq
humanH. sapiensGenome 40220.05 56583.55 44648.32 37358.37 54755.67 87196.64 37706.77 54655.79 51642.37
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 82076.05 89380.14 53663.33 81747.84 91599.99 119536.39 81077.64 87125.73 65047.45

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 40220.05 37358.37 37706.77 -0.11 -0.09 0.01
7h 56583.55 54755.67 54655.79 -0.05 -0.05 -0.0
23h 44648.32 87196.64 51642.37 0.97 0.21 -0.76

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 40220.05 56583.55 44648.32 0.49 0.15 -0.34
Ebov 37358.37 54755.67 87196.64 0.55 1.22 0.67
Marv 37706.77 54655.79 51642.37 0.54 0.45 -0.08

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA