AGAP2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
AGAP2 PIKE,GGAP2,Cnt-g1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 NM_014770 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The gene AGAP2 is weakly expressed in bat without significant changes in expression profile.

The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. (provided by RefSeq, Aug 2011)

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome3 4 4 2 5 8 5 3 9
Read_Max
batR. aegyptiacusTranscriptome 29 23 29 30 30 34 23 34 58
Read_Max
bat_genomeR. aegyptiacusGenome 26 32 22 21 26 14 14 47 51
DESeq
humanH. sapiensGenome 33.47 28.54 28.8 20.39 27.01 57.58 34.33 25.78 101.04
DESeq
batR. aegyptiacusTranscriptome 258.92 312.34 444.42 381.92 459.84 474.49 276.88 394.28 647.41
DESeq
bat_genomeR. aegyptiacusGenome 340.32 449.04 536.69 394.01 511.19 522.16 323.87 455.94 752.59

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 33.47 20.39 34.33 -0.72 0.04 0.75
7h 28.54 27.01 25.78 -0.08 -0.15 -0.07
23h 28.8 57.58 101.04 1.0 1.81 0.81

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 33.47 28.54 28.8 -0.23 -0.22 0.01
Ebov 20.39 27.01 57.58 0.41 1.5 1.09
Marv 34.33 25.78 101.04 -0.41 1.56 1.97

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 258.92 381.92 276.88 0.56 0.1 -0.46
7h 312.34 459.84 394.28 0.56 0.34 -0.22
23h 444.42 474.49 647.41 0.09 0.54 0.45

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 258.92 312.34 444.42 0.27 0.78 0.51
Ebov 381.92 459.84 474.49 0.27 0.31 0.05
Marv 276.88 394.28 647.41 0.51 1.23 0.72