CHMP2B
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| CHMP2B | Charged Multivesicular Body Protein 2B, Chromatin Modifying Protein 2B, CHMP2.5,DKFZP564O123, VPS2B | charged multivesicular body protein 2B | NM_014043 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. Expressed in all samples, some variation in expression level
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 147 | 138 | 146 | 168 | 202 | 172 | 183 | 179 | 148 |
Read_Max |  | R. aegyptiacus | Transcriptome | 177 | 169 | 101 | 148 | 125 | 118 | 105 | 217 | 194 |
Read_Max |  | R. aegyptiacus | Genome | 197 | 158 | 96 | 171 | 114 | 85 | 107 | 259 | 229 |
DESeq | | H. sapiens | Genome | 1409.52 | 1412.5 | 1528.96 | 1455.37 | 1515.53 | 1644.59 | 1543.13 | 1320.73 | 1637.46 |
DESeq | | R. aegyptiacus | Transcriptome | 226.16 | 240.63 | 195.22 | 205.19 | 184.98 | 206.31 | 193.45 | 233.99 | 266.04 |
DESeq | | R. aegyptiacus | Genome | 1033.85 | 1000.3 | 836.83 | 1049.7 | 1068.14 | 1010.39 | 1157.14 | 1070.48 | 1201.24 |