CHMP2B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CHMP2B Charged Multivesicular Body Protein 2B, Chromatin Modifying Protein 2B, CHMP2.5,DKFZP564O123, VPS2B charged multivesicular body protein 2B NM_014043 pdf

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Description

This gene encodes a component of the heteromeric ESCRT-III complex (Endosomal Sorting Complex Required for Transport III) that functions in the recycling or degradation of cell surface receptors. ESCRT-III functions in the concentration and invagination of ubiquitinated endosomal cargos into intralumenal vesicles. The protein encoded by this gene is found as a monomer in the cytosol or as an oligomer in ESCRT-III complexes on endosomal membranes. It is expressed in neurons of all major regions of the brain. Mutations in this gene result in one form of familial frontotemporal lobar degeneration. Expressed in all samples, some variation in expression level

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome147 138 146 168 202 172 183 179 148
Read_Max
batR. aegyptiacusTranscriptome 177 169 101 148 125 118 105 217 194
Read_Max
bat_genomeR. aegyptiacusGenome 197 158 96 171 114 85 107 259 229
DESeq
humanH. sapiensGenome 1409.52 1412.5 1528.96 1455.37 1515.53 1644.59 1543.13 1320.73 1637.46
DESeq
batR. aegyptiacusTranscriptome 226.16 240.63 195.22 205.19 184.98 206.31 193.45 233.99 266.04
DESeq
bat_genomeR. aegyptiacusGenome 1033.85 1000.3 836.83 1049.7 1068.14 1010.39 1157.14 1070.48 1201.24

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1409.52 1455.37 1543.13 0.05 0.13 0.08
7h 1412.5 1515.53 1320.73 0.1 -0.1 -0.2
23h 1528.96 1644.59 1637.46 0.11 0.1 -0.01

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1409.52 1412.5 1528.96 0.0 0.12 0.11
Ebov 1455.37 1515.53 1644.59 0.06 0.18 0.12
Marv 1543.13 1320.73 1637.46 -0.22 0.09 0.31

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 226.16 205.19 193.45 -0.14 -0.23 -0.08
7h 240.63 184.98 233.99 -0.38 -0.04 0.34
23h 195.22 206.31 266.04 0.08 0.45 0.37

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 226.16 240.63 195.22 0.09 -0.21 -0.3
Ebov 205.19 184.98 206.31 -0.15 0.01 0.16
Marv 193.45 233.99 266.04 0.27 0.46 0.19