RET
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| RET | PTC, CDHF12, RET51, CDHR16 | ret proto-oncogene | NM_020975 |  |
NONE | NONE | NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. No expression in human and no bat homolog was found.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 0 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | 2 | 1 | 1 | 1 | NA | NA | 1 |
Read_Max |  | R. aegyptiacus | Genome | 0 | 1 | 1 | 0 | 2 | 2 | 0 | 3 | 5 |
DESeq | | H. sapiens | Genome | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
DESeq | | R. aegyptiacus | Transcriptome | 1.0 | 1.0 | 3.44 | 1.92 | 2.1 | 2.28 | 1.0 | 1.0 | 1.87 |
DESeq | | R. aegyptiacus | Genome | 0.0 | 4.56 | 2.23 | 0.0 | 2.23 | 9.14 | 0.0 | 6.34 | 28.25 |