RET

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RET PTC, CDHF12, RET51, CDHR16 ret proto-oncogene NM_020975 pdf NONE NONE NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. No expression in human and no bat homolog was found.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome0 0 0 1 0 0 0 1 0
Read_Max
batR. aegyptiacusTranscriptome NA NA 2 1 1 1 NA NA 1
Read_Max
bat_genomeR. aegyptiacusGenome 0 1 1 0 2 2 0 3 5
DESeq
humanH. sapiensGenome 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0 1.0
DESeq
batR. aegyptiacusTranscriptome 1.0 1.0 3.44 1.92 2.1 2.28 1.0 1.0 1.87
DESeq
bat_genomeR. aegyptiacusGenome 0.0 4.56 2.23 0.0 2.23 9.14 0.0 6.34 28.25

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 1.0 1.0 0.0 0.0 0.0
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 1.0 1.0 1.0 0.0 0.0 0.0

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 1.0 0.0 0.0 0.0
Ebov 1.0 1.0 1.0 0.0 0.0 0.0
Marv 1.0 1.0 1.0 0.0 0.0 0.0

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 1.92 1.0 0.94 0.0 -0.94
7h 1.0 2.1 1.0 1.07 0.0 -1.07
23h 3.44 2.28 1.87 -0.59 -0.88 -0.29

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 3.44 0.0 1.78 1.78
Ebov 1.92 2.1 2.28 0.13 0.25 0.12
Marv 1.0 1.0 1.87 0.0 0.9 0.9