ARF6

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ARF6 ADP-ribosylation factor 6 NM_001663 pdf

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Description

Homo sapiens ADP-ribosylation factor 6 (ARF6), mRNA. This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008].

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome437 468 315 376 482 725 476 564 319
Read_Max
batR. aegyptiacusTranscriptome 728 598 511 592 608 868 651 758 911
Read_Max
bat_genomeR. aegyptiacusGenome 930 825 518 731 570 542 655 1074 1086
DESeq
humanH. sapiensGenome 5532.6 5582.76 4826.13 5245.86 5024.22 6083.19 5157.21 5032.91 4901.67
DESeq
batR. aegyptiacusTranscriptome 2234.09 2124.09 2309.7 2118.94 2369.68 2720.06 2739.74 2277.2 2613.76
DESeq
bat_genomeR. aegyptiacusGenome 8287.96 8340.11 7370.83 8093.42 8824.15 10430.23 9927.37 8209.37 9284.54

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 5532.6 5245.86 5157.21 -0.08 -0.1 -0.02
7h 5582.76 5024.22 5032.91 -0.15 -0.15 0.0
23h 4826.13 6083.19 4901.67 0.33 0.02 -0.31

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 5532.6 5582.76 4826.13 0.01 -0.2 -0.21
Ebov 5245.86 5024.22 6083.19 -0.06 0.21 0.28
Marv 5157.21 5032.91 4901.67 -0.04 -0.07 -0.04

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2234.09 2118.94 2739.74 -0.08 0.29 0.37
7h 2124.09 2369.68 2277.2 0.16 0.1 -0.06
23h 2309.7 2720.06 2613.76 0.24 0.18 -0.06

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2234.09 2124.09 2309.7 -0.07 0.05 0.12
Ebov 2118.94 2369.68 2720.06 0.16 0.36 0.2
Marv 2739.74 2277.2 2613.76 -0.27 -0.07 0.2