CLTA
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| CLTA | LCA,Lca | clathrin, light chain A | NM_007096 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. The gene is upregulated in human EBOV. The bat homolog is not significantly differentially expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 355 | 306 | 311 | 321 | 437 | 717 | 427 | 467 | 433 |
Read_Max |  | R. aegyptiacus | Transcriptome | 566 | 593 | 369 | 488 | 397 | 437 | 381 | 516 | 451 |
Read_Max |  | R. aegyptiacus | Genome | 623 | 501 | 319 | 546 | 318 | 261 | 320 | 589 | 492 |
DESeq | | H. sapiens | Genome | 1828.63 | 1565.49 | 1661.0 | 1691.49 | 1676.49 | 2930.24 | 1757.16 | 1831.51 | 2271.38 |
DESeq | | R. aegyptiacus | Transcriptome | 1847.63 | 2096.86 | 2113.04 | 1887.28 | 1939.31 | 2129.8 | 1941.04 | 1855.84 | 1918.36 |
DESeq | | R. aegyptiacus | Genome | 2272.23 | 2430.48 | 2516.08 | 2671.14 | 2452.15 | 2690.45 | 2336.78 | 2452.58 | 2259.49 |