SRC
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| SRC | ASV, c-src | SRC proto-oncogene, non-receptor tyrosine kinase | NM_005417 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC). This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 37 | 83 | 81 | 62 | 76 | 169 | 80 | 114 | 120 |
Read_Max |  | R. aegyptiacus | Transcriptome | 279 | 285 | 190 | 227 | 190 | 231 | 187 | 278 | 247 |
Read_Max |  | R. aegyptiacus | Genome | 294 | 225 | 156 | 277 | 153 | 129 | 147 | 327 | 265 |
DESeq | | H. sapiens | Genome | 786.45 | 1194.25 | 1241.04 | 1028.76 | 1064.34 | 2136.74 | 994.87 | 1398.26 | 2136.55 |
DESeq | | R. aegyptiacus | Transcriptome | 2382.8 | 2488.07 | 2202.21 | 2164.72 | 2007.2 | 2190.11 | 2022.24 | 2421.79 | 2001.46 |
DESeq | | R. aegyptiacus | Genome | 4329.61 | 3648.91 | 3647.48 | 4589.82 | 3764.72 | 4032.41 | 4020.2 | 3895.74 | 3509.53 |