RUFY1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RUFY1 RABIP4,FLJ22251, ZFYVE12, RABIP4 RUN and FYVE domain containing 1 NM_001040451 pdf NONE

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Description

The fene RUFY1 is weakly expressed in human and bat datasets but without significant changes in expression levels. This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. (provided by RefSeq, Dec 2011)

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome47 76 54 55 68 154 55 93 50
Read_Max
batR. aegyptiacusTranscriptome 63 80 61 58 54 101 64 69 81
Read_Max
bat_genomeR. aegyptiacusGenome 63 46 45 67 42 49 46 83 74
DESeq
humanH. sapiensGenome 734.69 944.38 864.76 809.74 791.19 2064.37 725.57 897.07 783.89
DESeq
batR. aegyptiacusTranscriptome 649.59 768.91 532.37 578.79 658.05 854.32 665.11 606.61 650.91
DESeq
bat_genomeR. aegyptiacusGenome 743.37 674.47 685.09 892.69 748.93 932.06 778.18 708.1 733.76

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 734.69 809.74 725.57 0.14 -0.02 -0.16
7h 944.38 791.19 897.07 -0.26 -0.07 0.18
23h 864.76 2064.37 783.89 1.26 -0.14 -1.4

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 734.69 944.38 864.76 0.36 0.24 -0.13
Ebov 809.74 791.19 2064.37 -0.03 1.35 1.38
Marv 725.57 897.07 783.89 0.31 0.11 -0.19

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 649.59 578.79 665.11 -0.17 0.03 0.2
7h 768.91 658.05 606.61 -0.22 -0.34 -0.12
23h 532.37 854.32 650.91 0.68 0.29 -0.39

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 649.59 768.91 532.37 0.24 -0.29 -0.53
Ebov 578.79 658.05 854.32 0.19 0.56 0.38
Marv 665.11 606.61 650.91 -0.13 -0.03 0.1