ACTR2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ACTR2 Arp2,ARP2 ARP2 actin-related protein 2 homolog (yeast) NM_001005386 pdf

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Description

The gene ACTR2 is expressed throughout human and bat datasets without significant changes in expression levels. The specific function of this gene has not yet been determined; however, the protein it encodes is known to be a major constituent of the ARP2/3 complex. This complex is located at the cell surface and is essential to cell shape and motility through lamellipodial actin assembly and protrusion. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Jul 2008)

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome962 1123 1177 1001 1598 1318 1275 1641 913
Read_Max
batR. aegyptiacusTranscriptome 3190 2772 1486 2508 2242 2035 2822 3012 2175
Read_Max
bat_genomeR. aegyptiacusGenome 3642 2623 1381 2820 1974 1252 2381 3495 2489
DESeq
humanH. sapiensGenome 13600.16 13259.35 14905.28 14494.52 14527.62 13969.51 13709.08 12680.3 13411.25
DESeq
batR. aegyptiacusTranscriptome 23466.96 21673.0 14648.45 19070.71 19128.94 16541.21 24205.84 19325.19 14796.7
DESeq
bat_genomeR. aegyptiacusGenome 34057.63 27232.69 19863.08 33774.9 28408.96 25515.54 36879.03 27627.82 22031.52

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 13600.16 14494.52 13709.08 0.09 0.01 -0.08
7h 13259.35 14527.62 12680.3 0.13 -0.06 -0.2
23h 14905.28 13969.51 13411.25 -0.09 -0.15 -0.06

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 13600.16 13259.35 14905.28 -0.04 0.13 0.17
Ebov 14494.52 14527.62 13969.51 0.0 -0.05 -0.06
Marv 13709.08 12680.3 13411.25 -0.11 -0.03 0.08

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 23466.96 19070.71 24205.84 -0.3 0.04 0.34
7h 21673.0 19128.94 19325.19 -0.18 -0.17 0.01
23h 14648.45 16541.21 14796.7 0.18 0.01 -0.16

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 23466.96 21673.0 14648.45 -0.11 -0.68 -0.57
Ebov 19070.71 19128.94 16541.21 0.0 -0.21 -0.21
Marv 24205.84 19325.19 14796.7 -0.32 -0.71 -0.39