TICAM1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| TICAM1 | B3Y691, NM_182919, NP_891549, O75532, PRVTIRB, Q86XP8, Q8IUC6, Q96GA0, TCAM1_HUMAN, TRIF, uc002mbi.3,TRIF, TICAM-1, MGC35334 | toll-like receptor adaptor molecule 1 | NM_014261 |  |
NONE |  |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes an adaptor protein containing a Toll/interleukin-1 receptor (TIR) homology domain, which is an intracellular signaling domain that mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components. This protein is involved in native immunity against invading pathogens. It specifically interacts with toll-like receptor 3, but not with other TLRs, and this association mediates dsRNA induction of interferon-beta through activation of nuclear factor kappa-B, during an antiviral immune response. This gene is not differentially expressed.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 8 | 9 | 10 | 12 | 12 | 26 | 8 | 12 | 16 |
Read_Max |  | R. aegyptiacus | Transcriptome | 34 | 48 | 26 | 33 | 29 | 36 | 28 | 34 | 44 |
Read_Max |  | R. aegyptiacus | Genome | 41 | 44 | 30 | 41 | 25 | 25 | 23 | 50 | 48 |
DESeq | | H. sapiens | Genome | 97.4 | 87.69 | 94.33 | 105.94 | 83.92 | 237.87 | 75.56 | 114.51 | 192.37 |
DESeq | | R. aegyptiacus | Transcriptome | 295.05 | 265.14 | 319.82 | 323.32 | 314.2 | 416.75 | 324.71 | 286.04 | 340.39 |
DESeq | | R. aegyptiacus | Genome | 397.04 | 405.23 | 446.31 | 379.19 | 426.36 | 518.25 | 413.83 | 357.62 | 452.93 |