HECTD1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
HECTD1 EULIR, KIAA1131,KIAA1131 HECT domain containing E3 ubiquitin protein ligase 1 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Probable E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. May be required for development of the head mesenchyme and neural tube closure (By similarity). After 7 hours of infection with Marburg virus, the expression is upregulated in bat. In contrast the expression is slightly downregulated 23 hours after Marburg virus infection in bat as well as Hu7.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome1361 1445 1071 1185 1594 1550 1408 1460 773
Read_Max
batR. aegyptiacusTranscriptome 551 461 275 499 424 483 419 567 430
Read_Max
bat_genomeR. aegyptiacusGenome 630 534 228 470 359 275 361 647 465
DESeq
humanH. sapiensGenome 47203.81 50975.27 46343.08 50573.19 55293.03 53607.72 45603.37 44532.01 35880.18
DESeq
batR. aegyptiacusTranscriptome 18928.52 15005.11 11771.73 17257.69 17863.01 18301.74 19032.04 15988.96 12918.7
DESeq
bat_genomeR. aegyptiacusGenome 21373.03 18962.85 12281.37 17998.86 20276.8 20972.72 21578.65 17206.93 14339.5

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 47203.81 50573.19 45603.37 0.1 -0.05 -0.15
7h 50975.27 55293.03 44532.01 0.12 -0.19 -0.31
23h 46343.08 53607.72 35880.18 0.21 -0.37 -0.58

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 47203.81 50975.27 46343.08 0.11 -0.03 -0.14
Ebov 50573.19 55293.03 53607.72 0.13 0.08 -0.04
Marv 45603.37 44532.01 35880.18 -0.03 -0.35 -0.31

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 18928.52 17257.69 19032.04 -0.13 0.01 0.14
7h 15005.11 17863.01 15988.96 0.25 0.09 -0.16
23h 11771.73 18301.74 12918.7 0.64 0.13 -0.5

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 18928.52 15005.11 11771.73 -0.34 -0.69 -0.35
Ebov 17257.69 17863.01 18301.74 0.05 0.08 0.04
Marv 19032.04 15988.96 12918.7 -0.25 -0.56 -0.31