IRF1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| IRF1 | MAR | interferon regulatory factor 1 | NM_002198 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
IRF1 encodes interferon regulatory factor 1, a member of the interferon regulatory transcription factor (IRF) family. IRF1 serves as an activator of interferons alpha and beta transcription, and in mouse it has been shown to be required for double-stranded RNA induction of these genes. IRF1 also functions as a transcription activator of genes induced by interferons alpha, beta, and gamma. Further, IRF1 has been shown to play roles in regulating apoptosis and tumor-suppressoion.
upregulated in bats after 23 hrs ebola and marburg but same pattern in mock sample
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 7 | 10 | 8 | 13 | 7 | 11 | 8 | 7 | 10 |
Read_Max |  | R. aegyptiacus | Transcriptome | 15 | 20 | 35 | 28 | 39 | 24 | 9 | 11 | 33 |
Read_Max |  | R. aegyptiacus | Genome | 28 | 28 | 46 | 19 | 23 | 34 | 15 | 32 | 69 |
DESeq | | H. sapiens | Genome | 33.47 | 42.81 | 49.65 | 86.55 | 32.71 | 93.11 | 65.91 | 40.17 | 90.16 |
DESeq | | R. aegyptiacus | Transcriptome | 37.13 | 52.74 | 139.03 | 63.27 | 98.46 | 81.84 | 28.81 | 32.4 | 111.21 |
DESeq | | R. aegyptiacus | Genome | 151.25 | 214.48 | 480.9 | 136.27 | 219.88 | 471.25 | 122.57 | 154.62 | 478.61 |