NUP153

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
NUP153 F6QR24, F6QR24_HUMAN, NM_001278209, NP_001265138, uc011dje.1,HNUP153 nucleoporin 153kDa pdf

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Description

Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.

This gene is not differentially expressed.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome679 683 507 621 780 952 908 884 453
Read_Max
batR. aegyptiacusTranscriptome 569 410 303 392 348 425 389 459 444
Read_Max
bat_genomeR. aegyptiacusGenome 636 408 255 400 304 244 325 569 485
DESeq
humanH. sapiensGenome 11887.2 11806.03 9894.5 13466.76 10946.57 15426.24 13481.88 12578.78 10942.97
DESeq
batR. aegyptiacusTranscriptome 7078.34 5970.88 5240.17 6616.7 6445.6 6618.37 6959.1 6308.28 5217.76
DESeq
bat_genomeR. aegyptiacusGenome 8242.41 7845.44 5906.93 7346.88 7535.02 7547.88 8159.6 7314.93 5962.52

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 11887.2 13466.76 13481.88 0.18 0.18 0.0
7h 11806.03 10946.57 12578.78 -0.11 0.09 0.2
23h 9894.5 15426.24 10942.97 0.64 0.15 -0.5

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 11887.2 11806.03 9894.5 -0.01 -0.26 -0.25
Ebov 13466.76 10946.57 15426.24 -0.3 0.2 0.49
Marv 13481.88 12578.78 10942.97 -0.1 -0.3 -0.2

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7078.34 6616.7 6959.1 -0.1 -0.02 0.07
7h 5970.88 6445.6 6308.28 0.11 0.08 -0.03
23h 5240.17 6618.37 5217.76 0.34 -0.01 -0.34

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7078.34 5970.88 5240.17 -0.25 -0.43 -0.19
Ebov 6616.7 6445.6 6618.37 -0.04 0.0 0.04
Marv 6959.1 6308.28 5217.76 -0.14 -0.42 -0.27