RBBP6
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| RBBP6 | PACT, MY038, P2P-R, RBQ-1, SNAMA,P2P-R, PACT | retinoblastoma binding protein 6 | NM_006910 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
upregulated in humans during ebola infection
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 178 | 196 | 226 | 123 | 322 | 533 | 186 | 255 | 185 |
Read_Max |  | R. aegyptiacus | Transcriptome | 195 | 146 | 148 | 131 | 144 | 273 | 159 | 165 | 193 |
Read_Max |  | R. aegyptiacus | Genome | 237 | 147 | 125 | 149 | 126 | 160 | 133 | 199 | 215 |
DESeq | | H. sapiens | Genome | 5191.63 | 5541.97 | 5875.54 | 4285.41 | 6649.31 | 11679.81 | 4365.09 | 5600.45 | 5310.51 |
DESeq | | R. aegyptiacus | Transcriptome | 3308.63 | 3449.31 | 2974.22 | 2537.4 | 3033.3 | 4589.66 | 3180.26 | 2470.54 | 2770.33 |
DESeq | | R. aegyptiacus | Genome | 4653.6 | 3637.96 | 3930.88 | 4855.46 | 4135.28 | 5771.22 | 4423.91 | 3557.16 | 3704.74 |