NUP107

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
NUP107 NUP84 nucleoporin 107kDa NM_020401 pdf

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Description

The gene NUP107 is moderately expressed in all human and bat datatsets, furthermore infected cell lines are down regulated at 23h after infection. This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. (provided by RefSeq, Jul 2008)

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome485 509 458 459 733 366 593 698 328
Read_Max
batR. aegyptiacusTranscriptome 333 393 217 270 244 230 313 282 216
Read_Max
bat_genomeR. aegyptiacusGenome 329 240 148 282 171 115 202 309 180
DESeq
humanH. sapiensGenome 4564.5 5035.09 5265.95 5016.58 5581.91 3817.17 4758.08 4723.56 4223.17
DESeq
batR. aegyptiacusTranscriptome 3187.65 3210.59 1873.62 3074.9 3502.0 2319.71 3679.73 3123.24 2085.43
DESeq
bat_genomeR. aegyptiacusGenome 2979.51 2702.46 1563.2 3141.19 3007.98 2173.51 3367.97 2760.24 1842.52

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4564.5 5016.58 4758.08 0.14 0.06 -0.08
7h 5035.09 5581.91 4723.56 0.15 -0.09 -0.24
23h 5265.95 3817.17 4223.17 -0.46 -0.32 0.15

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4564.5 5035.09 5265.95 0.14 0.21 0.06
Ebov 5016.58 5581.91 3817.17 0.15 -0.39 -0.55
Marv 4758.08 4723.56 4223.17 -0.01 -0.17 -0.16

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3187.65 3074.9 3679.73 -0.05 0.21 0.26
7h 3210.59 3502.0 3123.24 0.13 -0.04 -0.17
23h 1873.62 2319.71 2085.43 0.31 0.15 -0.15

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3187.65 3210.59 1873.62 0.01 -0.77 -0.78
Ebov 3074.9 3502.0 2319.71 0.19 -0.41 -0.59
Marv 3679.73 3123.24 2085.43 -0.24 -0.82 -0.58