MLKL

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
MLKL	hMLKL,FLJ34389	mixed lineage kinase domain-like	NM_152649	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The mixed lineage kinase domain-like is involved in the TNF signaling pathway. The expression in human in the analyzed samples was very low. In bat samples it did not particularly show differential expression.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	2	1	2	1	1	2	1	2	3
Read_Max		R. aegyptiacus	Transcriptome	76	71	45	74	66	71	64	90	96
Read_Max		R. aegyptiacus	Genome	77	72	38	73	59	41	58	112	111
DESeq		H. sapiens	Genome	7.09	2.02	7.95	5.56	2.63	6.26	6.26	4.2	16.22
DESeq		R. aegyptiacus	Transcriptome	495.84	473.91	394.33	486.3	521.17	474.49	554.98	481.85	507.46
DESeq		R. aegyptiacus	Genome	715.87	691.82	634.88	685.31	750.04	686.65	777.05	726.34	717.49

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	7.09	5.56	6.26	-0.35	-0.18	0.17
7h	2.02	2.63	4.2	0.38	1.06	0.68
23h	7.95	6.26	16.22	-0.34	1.03	1.37

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	7.09	2.02	7.95	-1.81	0.17	1.98
Ebov	5.56	2.63	6.26	-1.08	0.17	1.25
Marv	6.26	4.2	16.22	-0.58	1.37	1.95

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	495.84	486.3	554.98	-0.03	0.16	0.19
7h	473.91	521.17	481.85	0.14	0.02	-0.11
23h	394.33	474.49	507.46	0.27	0.36	0.1

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	495.84	473.91	394.33	-0.07	-0.33	-0.27
Ebov	486.3	521.17	474.49	0.1	-0.04	-0.14
Marv	554.98	481.85	507.46	-0.2	-0.13	0.07