MLKL

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MLKL hMLKL,FLJ34389 mixed lineage kinase domain-like NM_152649 pdf

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Description

The mixed lineage kinase domain-like is involved in the TNF signaling pathway. The expression in human in the analyzed samples was very low. In bat samples it did not particularly show differential expression.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome2 1 2 1 1 2 1 2 3
Read_Max
batR. aegyptiacusTranscriptome 76 71 45 74 66 71 64 90 96
Read_Max
bat_genomeR. aegyptiacusGenome 77 72 38 73 59 41 58 112 111
DESeq
humanH. sapiensGenome 7.09 2.02 7.95 5.56 2.63 6.26 6.26 4.2 16.22
DESeq
batR. aegyptiacusTranscriptome 495.84 473.91 394.33 486.3 521.17 474.49 554.98 481.85 507.46
DESeq
bat_genomeR. aegyptiacusGenome 715.87 691.82 634.88 685.31 750.04 686.65 777.05 726.34 717.49

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7.09 5.56 6.26 -0.35 -0.18 0.17
7h 2.02 2.63 4.2 0.38 1.06 0.68
23h 7.95 6.26 16.22 -0.34 1.03 1.37

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7.09 2.02 7.95 -1.81 0.17 1.98
Ebov 5.56 2.63 6.26 -1.08 0.17 1.25
Marv 6.26 4.2 16.22 -0.58 1.37 1.95

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 495.84 486.3 554.98 -0.03 0.16 0.19
7h 473.91 521.17 481.85 0.14 0.02 -0.11
23h 394.33 474.49 507.46 0.27 0.36 0.1

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 495.84 473.91 394.33 -0.07 -0.33 -0.27
Ebov 486.3 521.17 474.49 0.1 -0.04 -0.14
Marv 554.98 481.85 507.46 -0.2 -0.13 0.07