MAP2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MAP2 MAP2A,MAP2B,MAP2C, MAP2B, MAP2C microtubule-associated protein 2 NM_001039538 pdf

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Description

The gene MAP2 is weakly expressed throughout human datasets without significant changes in expression levels. This gene encodes a protein that belongs to the microtubule-associated protein family. The proteins of this family are thought to be involved in microtubule assembly, which is an essential step in neurogenesis. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dentrites, implicating a role in determining and stabilizing dentritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described. (provided by RefSeq, Jan 2010)

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome22 17 11 17 31 50 18 30 78
Read_Max
batR. aegyptiacusTranscriptome 2 3 NA NA 3 2 2 2 2
Read_Max
bat_genomeR. aegyptiacusGenome 3 2 2 3 2 2 3 4 2
DESeq
humanH. sapiensGenome 371.4 311.04 185.67 297.58 391.22 1036.63 343.11 506.99 2261.59
DESeq
batR. aegyptiacusTranscriptome 2.68 6.45 1.0 1.0 4.29 3.57 3.22 4.3 2.75
DESeq
bat_genomeR. aegyptiacusGenome 7.73 10.95 10.04 11.85 14.51 2.61 7.87 13.48 10.27

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 371.4 297.58 343.11 -0.32 -0.11 0.21
7h 311.04 391.22 506.99 0.33 0.7 0.37
23h 185.67 1036.63 2261.59 2.48 3.61 1.13

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 371.4 311.04 185.67 -0.26 -1.0 -0.74
Ebov 297.58 391.22 1036.63 0.39 1.8 1.41
Marv 343.11 506.99 2261.59 0.56 2.72 2.16

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.68 1.0 3.22 -1.42 0.26 1.69
7h 6.45 4.29 4.3 -0.59 -0.58 0.0
23h 1.0 3.57 2.75 1.84 1.46 -0.38

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.68 6.45 1.0 1.27 -1.42 -2.69
Ebov 1.0 4.29 3.57 2.1 1.84 -0.27
Marv 3.22 4.3 2.75 0.42 -0.23 -0.64