CALD1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CALD1 CAD, LCAD,CDM, H-CAD, L-CAD caldesmon 1 NM_033138 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The gene CALD1 is well expressed in human and very well expressed in bat datatsets. Furthermore expression levels in human in general rise while they decrease in bat for the ebola dataset. This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. (provided by RefSeq, Jul 2008)

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome1561 1980 2196 1617 2942 2861 2181 2542 2455
Read_Max
batR. aegyptiacusTranscriptome 7037 6274 5256 7231 5118 4673 5389 7485 7059
Read_Max
bat_genomeR. aegyptiacusGenome 15588 15669 8140 11152 9057 4854 8723 18320 13157
DESeq
humanH. sapiensGenome 20081.6 23223.51 25881.95 23186.52 27647.02 32367.42 24590.81 23919.96 31317.68
DESeq
batR. aegyptiacusTranscriptome 56579.42 50242.54 59313.94 56523.37 54555.1 42358.83 57219.83 58054.54 51793.38
DESeq
bat_genomeR. aegyptiacusGenome 137983.67 144906.98 130619.64 133952.15 146244.79 110688.32 147881.59 142885.69 128919.35

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 20081.6 23186.52 24590.81 0.21 0.29 0.08
7h 23223.51 27647.02 23919.96 0.25 0.04 -0.21
23h 25881.95 32367.42 31317.68 0.32 0.28 -0.05

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 20081.6 23223.51 25881.95 0.21 0.37 0.16
Ebov 23186.52 27647.02 32367.42 0.25 0.48 0.23
Marv 24590.81 23919.96 31317.68 -0.04 0.35 0.39

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 56579.42 56523.37 57219.83 -0.0 0.02 0.02
7h 50242.54 54555.1 58054.54 0.12 0.21 0.09
23h 59313.94 42358.83 51793.38 -0.49 -0.2 0.29

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 56579.42 50242.54 59313.94 -0.17 0.07 0.24
Ebov 56523.37 54555.1 42358.83 -0.05 -0.42 -0.37
Marv 57219.83 58054.54 51793.38 0.02 -0.14 -0.16