HIPK2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
HIPK2 Homeodomain Interacting Protein Kinase 2, Homeodomain-Interacting Protein Kinase 2, hHIPk2 homeodomain interacting protein kinase 2 NM_022740 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. Expressed in all samples, some variation in expression level.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome405 338 298 321 442 226 311 352 186
Read_Max
batR. aegyptiacusTranscriptome 192 151 123 152 152 137 137 154 130
Read_Max
bat_genomeR. aegyptiacusGenome 192 183 101 143 138 93 112 187 220
DESeq
humanH. sapiensGenome 18625.38 14973.75 14183.5 13929.88 15381.22 8611.08 12286.25 11330.99 10668.96
DESeq
batR. aegyptiacusTranscriptome 2367.68 1910.78 1916.37 2269.11 2291.93 1780.77 1935.47 1780.65 1634.08
DESeq
bat_genomeR. aegyptiacusGenome 2901.3 2842.1 2614.27 2354.16 3007.98 2589.93 2487.46 2214.7 2107.09

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 18625.38 13929.88 12286.25 -0.42 -0.6 -0.18
7h 14973.75 15381.22 11330.99 0.04 -0.4 -0.44
23h 14183.5 8611.08 10668.96 -0.72 -0.41 0.31

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 18625.38 14973.75 14183.5 -0.31 -0.39 -0.08
Ebov 13929.88 15381.22 8611.08 0.14 -0.69 -0.84
Marv 12286.25 11330.99 10668.96 -0.12 -0.2 -0.09

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2367.68 2269.11 1935.47 -0.06 -0.29 -0.23
7h 1910.78 2291.93 1780.65 0.26 -0.1 -0.36
23h 1916.37 1780.77 1634.08 -0.11 -0.23 -0.12

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2367.68 1910.78 1916.37 -0.31 -0.31 0.0
Ebov 2269.11 2291.93 1780.77 0.01 -0.35 -0.36
Marv 1935.47 1780.65 1634.08 -0.12 -0.24 -0.12