ARPC5

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ARPC5 p16-Arc, ARC16, dJ127C7.3 actin related protein 2/3 complex, subunit 5, 16kDa NM_005717 pdf NONE

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Description

The gene ARPC5 is expressed throughout all human and bat datasets. However while expression levels go down in human, they stay stable in bat. This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. (provided by RefSeq, Jul 2012)

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome557 569 393 584 601 336 686 833 521
Read_Max
batR. aegyptiacusTranscriptome 316 282 315 322 270 246 322 367 441
Read_Max
bat_genomeR. aegyptiacusGenome 387 382 277 279 268 210 266 509 500
DESeq
humanH. sapiensGenome 3522.31 3349.24 3232.64 3558.79 3525.14 2298.6 3563.33 3551.71 4884.27
DESeq
batR. aegyptiacusTranscriptome 886.51 877.83 1050.3 903.85 981.11 851.75 1108.96 970.14 1041.03
DESeq
bat_genomeR. aegyptiacusGenome 2662.39 3125.03 2850.81 2585.23 3204.42 3052.05 3454.56 3312.93 3398.22

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3522.31 3558.79 3563.33 0.01 0.02 0.0
7h 3349.24 3525.14 3551.71 0.07 0.08 0.01
23h 3232.64 2298.6 4884.27 -0.49 0.6 1.09

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3522.31 3349.24 3232.64 -0.07 -0.12 -0.05
Ebov 3558.79 3525.14 2298.6 -0.01 -0.63 -0.62
Marv 3563.33 3551.71 4884.27 -0.0 0.45 0.46

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 886.51 903.85 1108.96 0.03 0.32 0.3
7h 877.83 981.11 970.14 0.16 0.14 -0.02
23h 1050.3 851.75 1041.03 -0.3 -0.01 0.29

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 886.51 877.83 1050.3 -0.01 0.24 0.26
Ebov 903.85 981.11 851.75 0.12 -0.09 -0.2
Marv 1108.96 970.14 1041.03 -0.19 -0.09 0.1