NOD2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| NOD2 | BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1 | nucleotide-binding oligomerization domain containing 2 | NM_022162 |  |
NONE |  |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene is a member of the Nod1/Apaf-1 family and encodes a protein with two caspase recruitment (CARD) domains and six leucine-rich repeats (LRRs). The protein is primarily expressed in the peripheral blood leukocytes. It plays a role in the immune response to intracellular bacterial lipopolysaccharides (LPS) by recognizing the muramyl dipeptide (MDP) derived from them and activating the NFKB protein. Mutations in this gene have been associated with Crohn disease and Blau syndrome. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. This gene is not expressed in the investigated cell lines.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 2 | 1 | 2 | 1 | 0 | 0 | 2 | 0 | 1 |
Read_Max |  | R. aegyptiacus | Transcriptome | 2 | 4 | 3 | 3 | 2 | 4 | 4 | 2 | 2 |
Read_Max |  | R. aegyptiacus | Genome | 2 | 3 | 4 | 4 | 2 | 2 | 4 | 8 | 5 |
DESeq | | H. sapiens | Genome | 1.0 | 1.0 | 2.99 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
DESeq | | R. aegyptiacus | Transcriptome | 5.2 | 4.63 | 10.77 | 8.33 | 5.38 | 8.7 | 11.01 | 5.96 | 7.12 |
DESeq | | R. aegyptiacus | Genome | 9.45 | 26.47 | 41.28 | 8.89 | 29.02 | 24.8 | 24.74 | 25.37 | 39.38 |