PIK3R5
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| PIK3R5 | P101-PI3K, p101 | phosphoinositide-3-kinase, regulatory subunit 5 | NM_014308 |  |
NONE | NONE | NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. No expression and no bat homolog found.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 1 | 2 | 2 | 2 | 2 | 3 | 2 | 3 | 5 |
Read_Max |  | R. aegyptiacus | Transcriptome | 39 | 37 | 32 | 40 | 41 | 34 | 20 | 35 | 37 |
Read_Max |  | R. aegyptiacus | Genome | 47 | 37 | 30 | 29 | 31 | 21 | 24 | 42 | 48 |
DESeq | | H. sapiens | Genome | 3.03 | 7.12 | 10.93 | 13.55 | 3.44 | 3.63 | 3.63 | 8.19 | 7.52 |
DESeq | | R. aegyptiacus | Transcriptome | 343.78 | 426.71 | 536.03 | 422.21 | 417.13 | 438.56 | 304.69 | 416.58 | 492.59 |
DESeq | | R. aegyptiacus | Genome | 533.68 | 585.94 | 766.54 | 632.98 | 575.93 | 668.37 | 529.65 | 647.84 | 708.93 |