NFKBIE
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| NFKBIE | IKBE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. It is strongly upregulated after 23 hours of ebola virus infection and constantly expressed in bat.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 21 | 16 | 20 | 20 | 21 | 180 | 24 | 25 | 39 |
Read_Max |  | R. aegyptiacus | Transcriptome | 32 | 41 | 41 | 33 | 25 | 43 | 19 | 39 | 59 |
Read_Max |  | R. aegyptiacus | Genome | 34 | 31 | 28 | 34 | 21 | 28 | 17 | 49 | 55 |
DESeq | | H. sapiens | Genome | 199.9 | 167.24 | 149.92 | 261.08 | 169.28 | 1599.85 | 238.72 | 212.83 | 338.08 |
DESeq | | R. aegyptiacus | Transcriptome | 194.23 | 186.17 | 302.72 | 250.06 | 209.07 | 347.46 | 163.41 | 237.3 | 344.76 |
DESeq | | R. aegyptiacus | Genome | 256.1 | 314.88 | 363.74 | 265.63 | 271.22 | 483.0 | 230.53 | 289.43 | 446.08 |