AKT3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
AKT3 MPPH, MPPH2, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2,PKBG v-akt murine thymoma viral oncogene homolog 3 NM_181690 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The v-akt murine thymoma viral oncogene homolog 3 (EC:2.7.11.1) is involved in the MAPK, ErbB, Ras, Rap1, cGMP-PKG, cAMP, Chemokine, HIF-1, FoxO, mTOR, PI3K-Akt, VEGF, Toll-like receptor, T cell receptor, B cell receptor, TNF, Neurotrophin, Jak-STAT, Fc epsilon RI, Insulin, Estrogen, Prolactin, Thyroid hormone, Adipocytokine and AMPK signaling pathways. Also in Apoptosis, Adrenergic signaling in cardiomyocytes, Osteoclast differentiation, Focal adhesion, Tight junction, Signaling pathways regulating pluripotency of stem cells, Platelet activation, Fc gamma R-mediated phagocytosis, Cholinergic and Dopaminergic synapses, Progesterone-mediated oocyte maturation, Non-alcoholic fatty liver disease (NAFLD), Carbohydrate digestion and absorption, Chagas disease (American trypanosomiasis), Toxoplasmosis, Tuberculosis, Hepatitis C, Hepatitis B, Measles, Influenza A, HTLV-I infection, Epstein-Barr virus infection and Pathways in cancer.

It does not present a particularly interesting differential expression pattern in the samples analyzed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome7 13 10 8 17 16 8 15 8
Read_Max
batR. aegyptiacusTranscriptome 58 53 49 48 39 58 58 44 69
Read_Max
bat_genomeR. aegyptiacusGenome 186 149 113 152 108 121 159 177 260
DESeq
humanH. sapiensGenome 144.08 187.64 134.04 123.05 152.21 160.23 120.3 129.7 135.83
DESeq
batR. aegyptiacusTranscriptome 409.31 363.17 325.93 296.76 309.82 461.66 501.58 301.74 407.74
DESeq
bat_genomeR. aegyptiacusGenome 2395.98 1779.74 1864.46 2266.27 1959.93 2790.97 2739.36 1868.97 2253.5

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 144.08 123.05 120.3 -0.23 -0.26 -0.03
7h 187.64 152.21 129.7 -0.3 -0.53 -0.23
23h 134.04 160.23 135.83 0.26 0.02 -0.24

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 144.08 187.64 134.04 0.38 -0.1 -0.49
Ebov 123.05 152.21 160.23 0.31 0.38 0.07
Marv 120.3 129.7 135.83 0.11 0.18 0.07

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 409.31 296.76 501.58 -0.46 0.29 0.76
7h 363.17 309.82 301.74 -0.23 -0.27 -0.04
23h 325.93 461.66 407.74 0.5 0.32 -0.18

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 409.31 363.17 325.93 -0.17 -0.33 -0.16
Ebov 296.76 309.82 461.66 0.06 0.64 0.58
Marv 501.58 301.74 407.74 -0.73 -0.3 0.43