UBE2N

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
UBE2N	UbcH13,HEL-S-71,bc13,UbcH-ben, UBC13, MGC8489	ubiquitin-conjugating enzyme E2N	NM_003348	pdf

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Description

Homo sapiens ubiquitin-conjugating enzyme E2N (UBE2N), mRNA. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008].

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	631	632	605	657	853	645	775	912	612
Read_Max	R. aegyptiacus	Transcriptome	902	910	594	868	709	708	753	857	842
Read_Max	R. aegyptiacus	Genome	849	786	453	731	576	366	613	976	835
DESeq	H. sapiens	Genome	4612.19	3892.84	3560.28	4584.26	3735.7	2985.51	4270.36	3772.34	3986.13
DESeq	R. aegyptiacus	Transcriptome	2986.02	3071.71	2714.03	3076.73	3076.01	3008.78	3447.23	2881.16	2818.44
DESeq	R. aegyptiacus	Genome	5493.22	5394.88	4395.05	5635.57	5608.57	5517.97	6665.1	5317.5	5075.5

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	4612.19	4584.26	4270.36	-0.01	-0.11	-0.1
7h	3892.84	3735.7	3772.34	-0.06	-0.05	0.01
23h	3560.28	2985.51	3986.13	-0.25	0.16	0.42

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	4612.19	3892.84	3560.28	-0.24	-0.37	-0.13
Ebov	4584.26	3735.7	2985.51	-0.3	-0.62	-0.32
Marv	4270.36	3772.34	3986.13	-0.18	-0.1	0.08

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2986.02	3076.73	3447.23	0.04	0.21	0.16
7h	3071.71	3076.01	2881.16	0.0	-0.09	-0.09
23h	2714.03	3008.78	2818.44	0.15	0.05	-0.09

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2986.02	3071.71	2714.03	0.04	-0.14	-0.18
Ebov	3076.73	3076.01	3008.78	-0.0	-0.03	-0.03
Marv	3447.23	2881.16	2818.44	-0.26	-0.29	-0.03

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material