ITGA3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGA3 CD49C, GAP-B3, GAPB3, ILNEB, MSK18, VCA-2, VL3A, VLA3a,CD49c integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) NM_005501 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) is involved in the PI3K-Akt signaling pathway, Focal adhesion, ECM-receptor interaction, Hematopoietic cell lineage, Regulation of actin cytoskeleton, Pathways in cancer, Small cell lung cancer, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy.

There was practically no expression in the human samples, but in the samples from bats, there was slight upregulation in Marburg virus infection and slight downregulation in ebola infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 2 3 2 5 2 4 6 3
Read_Max
batR. aegyptiacusTranscriptome 243 250 154 169 138 134 111 184 261
Read_Max
bat_genomeR. aegyptiacusGenome 258 190 130 245 115 75 92 223 293
DESeq
humanH. sapiensGenome 26.37 11.2 3.98 13.55 13.19 6.26 21.18 31.38 27.1
DESeq
batR. aegyptiacusTranscriptome 2833.11 3289.56 3302.81 2969.6 2690.54 2264.53 2149.06 2742.36 4188.23
DESeq
bat_genomeR. aegyptiacusGenome 3678.19 3786.73 4282.35 4517.74 3530.33 3050.74 2894.55 3469.14 5447.09

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 26.37 13.55 21.18 -0.96 -0.32 0.64
7h 11.2 13.19 31.38 0.24 1.49 1.25
23h 3.98 6.26 27.1 0.65 2.77 2.11

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 26.37 11.2 3.98 -1.24 -2.73 -1.49
Ebov 13.55 13.19 6.26 -0.04 -1.11 -1.08
Marv 21.18 31.38 27.1 0.57 0.36 -0.21

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2833.11 2969.6 2149.06 0.07 -0.4 -0.47
7h 3289.56 2690.54 2742.36 -0.29 -0.26 0.03
23h 3302.81 2264.53 4188.23 -0.54 0.34 0.89

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2833.11 3289.56 3302.81 0.22 0.22 0.01
Ebov 2969.6 2690.54 2264.53 -0.14 -0.39 -0.25
Marv 2149.06 2742.36 4188.23 0.35 0.96 0.61